Mechanisms of DNA Damage Recognition
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- Basic cancer researchers, molecular geneticists, oncologists
- Professional and scholarly
Book Description
DNA damage responses are integral to the repair of DNA and initiation of checkpoints that maintain genomic stability.
Table of Contents
ATR biochemistry.- ATM biochemistry.- ATM biochemistry, Xenopus extracts.- ATR bioschemistry Xenopus extracts.- ATM/ATR signaling related topics and cell assays.- ATM, Brca1 cell based assays.- immunofluorescence-based techniques for looking at DSB signaling.- mouse modles.- mouse models.- mouse models.- checkpoint signaling at replication forks.- checkpoint adaptation.- checkpoint signaling.- chromatin and DSBs.- Brca2, Rad51 biochemistry.- signaling pathways and non-homologous, Xenopus extracts.- DNA PK and ATM DSB recognition.- DNA-PK/Ku DSB recognition.- NEJ,DSBR.- mismatch repair.- mismatch repair.- excision repair.- DSBR.- mismatch repair
